LactaViva is a dietary supplement — a microencapsulated probiotic based on the Lacticaseibacillus rhamnosus GG strain (ATCC 53103). It supports the restoration of gut microflora balance and normal digestion. The strain is manufactured by Probiotical S.p.A. (Italy).

Which probiotic strain is in LactaViva?

The active strain is Lacticaseibacillus rhamnosus GG (LGG, ATCC 53103), the most studied probiotic strain in the world with more than 2000 clinical studies. Each capsule contains ≥10 billion AFU of live cells; each sachet contains ≥5 billion AFU.

What is microencapsulation and why is it needed?

Microencapsulation is a protective shell around the live probiotic bacteria. It shields the strain from the harsh environment of the stomach and delivers the bacteria to the gut alive, where they are meant to work. Live cell counting is performed by flow cytometry (a validated variation of ISO 19344:2015).

For which conditions is the LGG strain used?

The Lacticaseibacillus rhamnosus GG strain is used to restore microflora balance during and after a course of antibiotics (antibiotic-associated diarrhea), in acute gastroenteritis, and for microbiome balance and digestive comfort (reducing episodes of gas and bloating). LactaViva is a dietary supplement, not a medicine; consult a doctor before use.

Where can I buy LactaViva in Uzbekistan?

LactaViva will soon be available in pharmacies across Uzbekistan. For availability and details, contact the exclusive distributor Sorrento Pharm at +998 71 230 95 86.

PROBIOTICS · Lacticaseibacillus rhamnosus GG

LactaViva

Q: How do I take LactaViva?

Capsules (adults): 1 capsule per day, preferably on an empty stomach. Sachets (children): 1–2 sticks per day — pour the contents into a glass, add room-temperature water, stir and drink immediately. Or as recommended by a doctor.

Live probiotics, sheltered inside microcapsules.
Gut health starts from within.

≥ 10 billion AFU ATCC 53103 Microencapsulated

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The range

One strain.
Two forms.

Capsules for adults and sachets for children — a premium LGG probiotic in a clean, recognisable design.

Sound familiar?

Bloating. Gas.
Heaviness. Diarrhea.

Antibiotics, stress and diet disrupt the balance of gut microflora. This imbalance is no small thing: it affects digestion, immunity and how you feel every day.

Antibiotic-associated diarrhea

A course of antibiotics washes out beneficial bacteria along with the pathogens.

Episodes of gas and bloating

Disrupted microflora struggles to handle fermentation and balance.

Microbiome imbalance

Stress and diet shift the gut ecosystem towards dysbiosis.

The active strain

Lacticaseibacillus
rhamnosus GG

ATCC 53103 · “LGG”

The most studied probiotic strain in the world. The very LGG on which the global evidence base of probiotics is built — from pediatrics to gastroenterology.

0clinical studies on the LGG strain

0AFU of live cells in every capsule

No.1most studied among probiotics

0shelf life · store below 25 °C

Technology

Microencapsulation.
Bacteria that arrive alive.

Live probiotic microorganisms are enclosed in a protective microcapsule. The shell shields the bacteria from a harsh environment and delivers them to the gut alive — right where they are meant to work.

The microcapsule protects the strain all the way to its site of action
≥ 10 billion AFU* of active cells per dose
HPMC shell · vegetarian capsule
ISO 19344:2015 — live cell counting by flow cytometry

*AFU — Active Fluorescent Units.

Microcapsule with live probiotic cells

Two dosage forms

For adults and for children

Adults

Capsules · No.10 / No.30

1 capsule per day, preferably on an empty stomach, or as recommended by a doctor.

≥ 10 billion AFU in every capsule
Vegetarian HPMC shell
10 or 30 capsules (1 or 3 blisters)

Children · convenient format

Sachets · No.10

1–2 sticks per day: pour the contents into a glass, add water (cold or room temperature) and drink immediately.

≥ 5 billion AFU in every sachet
Powder — dissolve in water
10 sachets per pack

Evidence base of the LGG strain

What the studies show

ESPGHAN · strong recommendation WGO · first-choice probiotic

23% → 9.6%

Antibiotic-associated diarrhea in children

Incidence during antibiotics is cut by more than half (NNT 8). A high dose delivers the maximum effect.

Szajewska et al., J Pediatr Gastroenterol Nutr, 2016 — ESPGHAN recommendation

No.1

Among probiotics — efficacy and tolerability

LGG ranked first both for efficacy against AAD and for tolerability in a large network meta-analysis.

Cai et al., United European Gastroenterol J, 2018 — 51 RCTs, 9,569 participants

−40%

Prevention of atopic dermatitis

The risk of eczema by age 2 with perinatal use (mother + infant) is significantly lower (RR 0.60).

Voigt & Lele, Am J Clin Dermatol, 2022 — meta-analysis of 11 RCTs

~1 day

Shorter duration of acute diarrhea in children

Meta-analyses show diarrhea shortened by ~24 hours on average and a shorter hospital stay.

Li et al. 2019 · McFarland et al. 2021 — meta-analyses

The data shown relate to the Lacticaseibacillus rhamnosus GG strain (ATCC 53103) from international publications. LactaViva is a dietary supplement, not a medicinal product. Consult a doctor before use.

Publications

Key clinical studies

Study	Type · size	Indication	Result
Cai et al., 2018United European Gastroenterol J	Network meta-analysis · 51 RCTs / 9,569	Antibiotic-associated diarrhea	LGG — No.1 for efficacy (OR 0.28) and No.1 for tolerability
Szajewska et al., 2016JPGN · ESPGHAN	Systematic review · 5 RCTs / 445 children	Prevention of AAD	Risk 23% → 9.6%, NNT 8 · strong recommendation
Szajewska & Kołodziej, 2015Aliment Pharmacol Ther	Meta-analysis · 12 RCTs / 1,499	AAD (children and adults)	AAD risk 22.4% → 12.3% (RR 0.49)
Voigt & Lele, 2022Am J Clin Dermatol	Meta-analysis · 11 RCTs	Prevention of atopic dermatitis	Risk of eczema by age 2 −40% (RR 0.60)
Li et al., 2019World J Gastroenterol	Meta-analysis · 19 RCTs	Acute diarrhea in children	Diarrhea shorter by ~24 h (high dose −31 h with rotavirus)
McFarland et al., 2021JPGN Reports	Meta-analysis · 22 RCTs / 4,059	Acute gastroenteritis	Diarrhea −1.7 days, hospital stay −1.1 days
Sharma et al., 2022Asian J Pharm Clin Res	Comparative RCT · 120 children	Acute diarrhea	Stool improvement by day 4 in 87.5% — higher than comparators
Gawrońska et al., 2007Aliment Pharmacol Ther	RCT · 104 children	Functional abdominal pain / IBS	NNT 7 (in the IBS subgroup — NNT 4)

The data relate to the LGG strain (ATCC 53103). Not all studies showed the same effect: the large RCT by Schnadower et al. (NEJM, 2018) found no benefit in the treatment of acute gastroenteritis. LactaViva is a dietary supplement, not a medicinal product.

Safety

Well tolerated

On par with placebo

The rate of adverse events in studies did not differ from placebo.

From the first months

The LGG strain has been studied in infants and in perinatal use in pregnant women.

No.1 for tolerability

First place among probiotics for tolerability in a network meta-analysis (2018).

Use with caution in severe immunodeficiency, in critically ill patients, or with a central venous catheter. Consult a doctor before use.

The product

LactaViva up close

Composition and use

Official information

Capsules

LactaViva No.10 / No.30

Composition: Microencapsulated probiotic microorganisms: Lacticaseibacillus rhamnosus GG (ATCC 53103), maltodextrin, anti-caking agent — silicon dioxide. Capsule shell: HPMC (hydroxypropyl methylcellulose).
Dose: ≥ 10 billion AFU* per capsule
Use: 1 capsule per day, preferably on an empty stomach, or as recommended by a doctor.
Presentation: 10 capsules per blister; 1 or 3 blisters in a carton with a leaflet.

Sachets

LactaViva No.10

Composition: Microencapsulated probiotic microorganisms: Lacticaseibacillus rhamnosus GG (ATCC 53103), maltodextrin, anti-caking agent — silicon dioxide.
Dose: ≥ 5 billion AFU* per sachet
Use: 1–2 sticks per day, regardless of meals (preferably on an empty stomach). Pour into a glass, add water, stir and drink immediately.
Presentation: 10 sachets in a carton with a leaflet.

Storage: in the original packaging, in a dry place protected from direct sunlight, below 25 °C. Keep away from children. Shelf life: 2 years.

*AFU — Active Fluorescent Units (live cell counting by flow cytometry, a validated variation of ISO 19344:2015).

Leaflet — Capsules (PDF) Leaflet — Sachets (PDF)

Manufacturing

Probiotical S.p.A.

Via E. Mattei 3, 28100 Novara, Italy.
Italian developer and manufacturer of probiotic strains.

Coming soon to pharmacies
in Uzbekistan

LactaViva — a premium probiotic based on the LGG strain. Ask for it at your pharmacy.

+998 71 230 95 86